Preheat your oven to 350°F (175°C). This sets the perfect stage for a golden, bubbly casserole.
Fill a large pot with salted water and bring it to a rolling boil. Add the elbow macaroni and cook according to package instructions until al dente. Once cooked, drain the pasta and set aside.
In a large skillet, heat the olive oil over medium heat. Add the ground turkey to the skillet, breaking it apart with a wooden spoon. Cook until the turkey is browned and fully cooked, about 5-7 minutes. Season the meat with garlic powder, onion powder, salt, and pepper to enhance the flavor.
Pour in the cream of chicken soup, ranch dressing, milk, and frozen mixed vegetables into the skillet. Stir everything together until thoroughly combined and cook for an additional 5 minutes, allowing the ingredients to heat through.
Incorporate the cooked macaroni and half of the shredded cheddar cheese into the turkey mixture, folding them together gently until all components are evenly mixed.
Carefully transfer the turkey and pasta mixture to a greased 9x13 inch baking dish. Sprinkle the remaining cheddar cheese on top for a gooey finish. If you desire a crispy topping, sprinkle breadcrumbs over the cheese.
Bake the casserole in the preheated oven for 25-30 minutes. It's ready when the cheese is bubbly and exhibits a lovely golden hue on top.
Notes
Serve directly from the baking dish for a rustic touch. Garnish with chopped fresh parsley for added color.